Cart
sales@molnova.com
HIV-1 inhibitor 18A
CAS No. 331261-50-8
HIV-1 inhibitor 18A ( Compound 18A )
Catalog No. M14111 CAS No. 331261-50-8
HIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 215 | Get Quote |
|
| 10MG | 296 | Get Quote |
|
| 25MG | 507 | Get Quote |
|
| 50MG | 712 | Get Quote |
|
| 100MG | 1008 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameHIV-1 inhibitor 18A
-
NoteResearch use only, not for human use.
-
Brief DescriptionHIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry.
-
DescriptionHIV-1 inhibitor 18A is a novel broad HIV-1 inhibitor that blocks envelope glycoprotein transitions critical for entry, specifically inhibits the entry of a wide range of HIV-1 isolates with mean IC50 of 6.4 uM; inhibits the CD4-induced disruption of quaternary structures at the trimer apex and the exposure of the gp41 HR1 coiled coil, does not interfere with CD4 or CCR5 binding.
-
SynonymsCompound 18A
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number331261-50-8
-
Formula Weight313.33
-
Molecular FormulaC14H11N5O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(N/N=C/C1=CC=C(O)C=C1)NC2=CC=CC3=NSN=C32
-
Chemical NameN-2,1,3-Benzothiadiazol-4-yl-2-[(4-hydroxyphenyl)methylene]-hydrazinecarboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Herschhorn A, et al. Nat Chem Biol. 2014 Oct;10(10):845-52.
2. Berinyuy E, et al. J Recept Signal Transduct Res. 2016;36(2):119-29.
2. Berinyuy E, et al. J Recept Signal Transduct Res. 2016;36(2):119-29.
molnova catalog
related products
-
Saquinavir
Apotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.
-
Doravirine
Doravirine (MK-1439, MK1439) is a novel, highly specific HIV-1 nonnucleoside reverse transcriptase inhibitor (NNRTI) with IC50 of 12, 9.7, and 9.7 nM against WT, K103N, and Y181C reverse transcriptase (RT) mutants, respectively.
-
MPG, HIV related
MPG, HIV related is 27-aa peptide, derived from both the nuclear localisation sequence of SV40 large T antigen and the fusion peptide domain of HIV-1 gp41 and is a potent delivery agent for the generalised delivery of nucleic acids and of oligonucleotides into cultured cells.
